Patents

"We ensure that our most promising research is adequately protected by studying its patentability before disseminating it to the international scientific community."
JUAN CARLOS ETAYO
HEAD OF INTELLECTUAL AND INDUSTRIAL PROPERTY

In this process of transferring our scientific research to society, the intellectual and industrial protection of our discoveries is important.

Since its inception, Cima has generated 135 inventions, at different stages of development, which have been subject to industrial protection.

From the Translational and Innovation Unit, we manage the inventions resulting from Cima's research, focused on both high-incidence and rare diseases.

Currently, 39 patents are active, 21 of them with Cima ownership. During the 2022-23 academic year, 6 patents generated at Cima have been registered.

Need more information?

If you are interested in collaborating with us, please contact our Translation and Innovation Unit.

187

active files
in Cima's portfolio

24

active patents
currently active patents

2

patented inventions
in the 2023-24 academic year

Recently patented inventions

Course With ownership No ownership Total generated CIMA
2018-2019 5 3 8
2019-2020 2 0 2
2020-2021 4 2 6
2021-2022 8 2 10
2022-2023 4 2 6
2023-2024 1 1 2

Learn about our patents


US20200087666

  • Title: Compounds targeting long noncoding RNA for the treatment of cancer
  • Inventors: Maite HUARTE MARTÍNEZ; Alejandro ATHIE CUERVO
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer; Lung cancer

WO2019243236

  • Title: New anticancer drug combinations
  • Inventors: Vicente José FRESQUET ARNAU; José Angel MARTÍNEZ CLIMENT; Julen OYARZABAL SANTAMARINA; Felipe PRÓSPER CARDOSO; Xabier AGUIRRE ENA; Marta DUEÑAS PORTO; Jesús M. PARAMIO GONZÁLEZ
  • Applicants: Fundación para la Investigación Médica Aplicada; Universidad de Navarra; Centro de Investigaciones Energéticas Medioambientales Y Tecnologías, O.A., M.P.
  • Indications: Cancer; Bladder cancer

WO2018146232

  • Title: In vitro method for the diagnosis of lung cancer
  • Inventors: Jackeline AGORRETA ARRAZUBI; Daniel AJONA MARTÍNEZ-POLO; Luis MONTUENGA BADÍA; María Josefa PAJARES VILLANDIEGO; Rubén PÍO OSÉS
  • Applicants: Fundación para la Investigación Médica Aplicada; Advanced Marker Discovery, S.L.
  • Indications: Diagnosis; Cancer; Lung cancer; Cancer, lung

WO2018077716

  • Title: FoxP3 binding peptides and uses thereof
  • Inventors: María Obdulia RABAL GRACIA; Julen OYARZABAL SANTAMARINA; Teresa LOZANO MOREDA; Juan José LASARTE SAGASTIBELZA; Inés Noelia CASARES LAGAR
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2015192981

  • Title: Novel compounds as dual inhibitors of histone methyltransferases and DNA methyltransferases
  • Inventors: Xabier AGUIRRE ENA; Julen OYARZABAL SANTAMARINA; Felipe PRÓSPER CARDOSO; María Obdulia RABAL GRACIA; Juan Roberto RODRÍGUEZ MADOZ; Edurne SAN JOSÉ ENÉRIZ
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer

WO2013143940

  • Title: New lung cancer molecular markers
  • Inventors: Daniel AJONA MARTÍNEZ-POLO; Leticia CORRALES PECINO; Luis MONTUENGA BADÍA; María Josefa PAJARES VILLANDIEGO; Rubén PÍO OSÉS
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications: Diagnosis; Cancer; Lung cancer

WO2024235848

  • Title:  Novel T cell receptors
  • Inventors: S Hervás Stubbs; E Vercher Herráez
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2024141549

  • Title: Riboswitches for gene therapy applications
  • Inventors: MP Fortes Alonso; F Pastor Rodríguez; B Moreno Bruna; E Rovira Barreira
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Terapia génica; Cáncer

    WO2024083988

  • Title: Nanobodies for cancer therapy
  • Inventors:  G González Sapienza; LM Vanrell Majó; C Smerdou Picazo; NR Silva Pilipich
  • Applicants: Fundación para la Investigación Médica Aplicada; Universidad de la República (UDELAR)
  • Indications: Immunotherapy; Cancer

WO2023170170

  • Title: New chimeric antigen receptor (CAR) cells and medical uses thereof
  • Inventors: Lasarte Sagastibelza JJ; Lozano Moreda T; Martín Otal C
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Immunotherapy; Cancer

WO2023064469

  • Title: Composition of mRNA-encoded IL15 fusion proteins and methods of use thereof
  • Inventors: Berraondo López P; Melero Bermejo IJ; Fernández Fernández M; Álvarez Rodríguez M; Frederick J; Bai A
  • Applicants: ModernaTX Inc.; Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

US20220313724

  • Title:Compositions for intratumoral administration and related methods
  • Inventors: Melero Bermejo IJ; Quintero Ortiz M; Álvarez Rodríguez M
  • Applicants: Highlight Therapeutics, S.L.; Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2024023313

  • Title: Genetically engineered mice models for multiple myeloma
  • Inventors: Martínez Climent JA; Larráyoz Ilundáin M; García Barchino MJ; Celay Leoz J
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer

WO2023170078

  • Title: Combined gene and radio therapy for the treatment of cancer
  • Inventors: Prieto Valtueña JM; Marco Martínez S; Honorato Cía B; Tenesaca Cayambe SM; Gould DJ
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2023170087

  • Title: Expression system for the treatment of cancer
  • Inventors: Prieto Valtueña JM; Marco Martínez S; Honorato Cía B; Tenesaca Cayambe SM; Gould DJ
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2018206125

  • Title: Human Porphobilinogen deaminase derived proteins and polynucleotides and uses thereof.
  • Inventors: Pedro BERRAONDO LÓPEZ; Antonio FONTANELLAS ROMÁ; Irantzu SERRANO MENDIOROZ.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Acute intermittent porphyria.

WO2017201346

  • Title: Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria.
  • Inventors: Christine LUKACS; Evan RACHLIN; Paolo MARTINI; Stephen HOGE; Kerry BENENATO; Vlad PRESNYAK; Lei JIANG; Iain MCFADYEN; Ellalahewage Sathyajith KUMARASINGHE; Antonio FONTANELLAS ROMÁ; Pedro BERRAONDO LÓPEZ; Matías Antonio ÁVILA ZARAGOZÁ; Lin Tung GUEY; Staci SABNIS.
  • Applicants: ModernaTX Inc.; Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Acute intermittent porphyria.

WO2016097219

  • Title: Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease and other conditions.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; Rubén HERNÁNDEZ ALCOCEBA; Oihana MURILLO SAUCA.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Wilson's disease.

WO2016097218

  • Title: Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease and other conditions.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; Rubén HERNÁNDEZ ALCOCEBA; Oihana MURILLO SAUCA.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Wilson's disease.

WO2022029322

  • Title: Gene therapy vector expressing CYP27A1 for the treatment of cerebro-tendinous xanthomatosis
  • Inventors: Rubén Hernández Alcoceba; Ana Ricobaraza Abarquero; González Aseguinolaza
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Cerebrotendinous xanthomatosis

WO2021028299

  • Title: Viral particles for use in treating synucleinopathies such as Parkinson's diseases by gene therapy.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; José Luis LANCIEGO PÉREZ; Ralph Michael LINDEN.
  • Applicants: Fundación para la Investigación Médica Aplicada; Consorcio Centro de Investigación Biomédica en Red del Área de Enfermedades Neurodegenerativas M.P., CIBERNED; Handl Therapeutics BV.
  • Indications: Central Nervous System; Parkinson's disease.

WO2021001377

  • Title: cPLA2e inducing agents and uses thereof.
  • Inventors: Ana María GARCÍA OSTA; María del Mar CUADRADO TEJEDOR; Marta PÉREZ GONZÁLEZ.
  • Applicants: Fundación para la Investigación Médica Aplicada; Universidad de Navarra.
  • Indications: Central Nervous System; Alzheimer's disease.

WO2014012964

  • Title: New antifibrinolytic compounds.
  • Inventors: Josune ORBE LOPATEGUI; Julen OYARZABAL SANTAMARINA; José Antonio PÁRAMO FERNÁNDEZ; José Antonio RODRÍGUEZ GARCÍA.
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications: Cardiovascular; Hemorrhages.

WO2024223955

  • Title: Medical device for deployment of a patch
  • Inventors: M Garmendia Barrenechea; A Gereka Goienetxe; AM Zaldua Huici; U Urtaza Sarrionandia; FL Prósper Cardoso; M García de Yébenes Castro; M Rodríguez Pérez; JJ Gavira Gómez; B Pelacho Samper; GM Abizanda Sarasa
  • Applicants: Leartiker S.Coop.; Universidad de Navarra; Fundación para la Investigación Médica Aplicada
  • Indications: Cardiac regeneration