Patents

"We ensure that our most promising research is adequately protected by studying its patentability before disseminating it to the international scientific community."
JUAN CARLOS ETAYO
HEAD OF INTELLECTUAL AND INDUSTRIAL PROPERTY

In this process of transferring our scientific research to society, the intellectual and industrial protection of our discoveries is important.

Since its inception, Cima has generated 112 inventions, at different stages of development, which have been subject to industrial protection.

From the Translational and Innovation Unit, we manage the inventions resulting from Cima's research, focused on both high-incidence and rare diseases.

Currently, 29 patents are active, 18 of them with Cima ownership. During the 2019-20 academic year, 2 patents generated at Cima have been registered.

Need more information?

If you are interested in collaborating with us, please contact our Translation and Innovation Unit.

174

active files
in Cima's portfolio

29

active patents
currently active patents

2

patented inventions
in the 2019-20 academic year

Patented inventions since 1997

Learn about our patents


US20200087666

  • Title: Compounds targeting long noncoding RNA for the treatment of cancer
  • Inventors: Maite HUARTE MARTÍNEZ; Alejandro ATHIE CUERVO
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer; Lung cancer

WO2019243236

  • Title: New anticancer drug combinations
  • Inventors: Vicente José FRESQUET ARNAU; José Angel MARTÍNEZ CLIMENT; Julen OYARZABAL SANTAMARINA; Felipe PRÓSPER CARDOSO; Xabier AGUIRRE ENA; Marta DUEÑAS PORTO; Jesús M. PARAMIO GONZÁLEZ
  • Applicants: Fundación para la Investigación Médica Aplicada; Universidad de Navarra; Centro de Investigaciones Energéticas Medioambientales Y Tecnologías, O.A., M.P.
  • Indications: Cancer; Bladder cancer

WO2018146232

  • Title: In vitro method for the diagnosis of lung cancer
  • Inventors: Jackeline AGORRETA ARRAZUBI; Daniel AJONA MARTÍNEZ-POLO; Luis MONTUENGA BADÍA; María Josefa PAJARES VILLANDIEGO; Rubén PÍO OSÉS
  • Applicants: Fundación para la Investigación Médica Aplicada; Advanced Marker Discovery, S.L.
  • Indications: Diagnosis; Cancer; Lung cancer; Cancer, lung

WO2018077716

  • Title: FoxP3 binding peptides and uses thereof
  • Inventors: María Obdulia RABAL GRACIA; Julen OYARZABAL SANTAMARINA; Teresa LOZANO MOREDA; Juan José LASARTE SAGASTIBELZA; Inés Noelia CASARES LAGAR
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Immunotherapy; Cancer

WO2017121712

  • Title: Method and kit for the diagnosis of lung cancer
  • Inventors: Juan SANDOVAL DEL AMOR; Luis MONTUENGA BADÍA; Ángel DÍAZ LAGARES; Jesús MÉNDEZ GONZÁLEZ; David HERVÁS MARÍN; Manel ESTELLER BADOSA
  • Applicants: Fundación para la Investigación Médica Aplicada; Institut d' Investigació Biomédica de Bellvitge (IDIBELL); Fund. para la Investigación del Hosp. Universitario y Politécnico La Fe de la Com. Valenciana
  • Indications: Diagnosis; Cancer; Lung cancer

WO2017085053

  • Title: Novel compounds as inhibitors of DNA methyltransferases
  • Inventors: Julen OYARZABAL SANTAMARINA; María Obdulia RABAL GRACIA; Juan Antonio SÁNCHEZ ARIAS; Felipe PRÓSPER CARDOSO; Xabier AGUIRRE ENA; Edurne SAN JOSÉ ENÉRIZ
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer

WO2015192981

  • Title: Novel compounds as dual inhibitors of histone methyltransferases and DNA methyltransferases
  • Inventors: Xabier AGUIRRE ENA; Julen OYARZABAL SANTAMARINA; Felipe PRÓSPER CARDOSO; María Obdulia RABAL GRACIA; Juan Roberto RODRÍGUEZ MADOZ; Edurne SAN JOSÉ ENÉRIZ
  • Applicants: Fundación para la Investigación Médica Aplicada
  • Indications: Cancer

WO2013143940

  • Title: New lung cancer molecular markers
  • Inventors: Daniel AJONA MARTÍNEZ-POLO; Leticia CORRALES PECINO; Luis MONTUENGA BADÍA; María Josefa PAJARES VILLANDIEGO; Rubén PÍO OSÉS
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications: Diagnosis; Cancer; Lung cancer

WO2011070214

  • Title: Conjugates and compositions for immunotherapy and antineoplastic treatment
  • Inventors: Pedro BERRAONDO LÓPEZ; Jessica FIORAVANTI; José MEDINA ECHEVERZ; Ignacio Javier MELERO BERMEJO; María del Carmen OCHOA NIETO; Francisco de Asis PALAZÓN GARCÍA; Silvia BULFONE-PAUS; Erwin Hans DUITMAN
  • Applicants: Proyecto de Biomedicina CIMA S.L.; Research Center Borstel
  • Indications: Immunotherapy; Cancer

WO2009150284

  • Title: Conjugates for the administration of biologically active compounds
  • Inventors: Pedro BERRAONDO LÓPEZ; Jesús María PRIETO VALTUEÑA; Jessica FIORAVANTI
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications:

WO2006134190

  • Title: Agents and methods based on the use of the EDA domain of fibronectin
  • Inventors: Juan José LASARTE SAGASTIBELZA; Marta GORRAIZ AYALA; Jesús María PRIETO VALTUEÑA; Claude LECLERC
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications: Immunotherapy; Cancer

WO2006086639

  • Title: Vascular/Lymphatic endothelial cells
  • Inventors: Felipe PRÓSPER CARDOSO; Carlos CLAVEL CLAVER; Xabier LÓPEZ-ARANGUREN; Catherine VERFALLIE; Aernout LUTTUN
  • Applicants: Proyecto de Biomedicina CIMA S.L.; The Regents of the University of Indicaciones.
  • Indications: Cell Therapy

WO2018206125

  • Title: Human Porphobilinogen deaminase derived proteins and polynucleotides and uses thereof.
  • Inventors: Pedro BERRAONDO LÓPEZ; Antonio FONTANELLAS ROMÁ; Irantzu SERRANO MENDIOROZ.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Acute intermittent porphyria.

WO2017201346

  • Title: Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria.
  • Inventors: Christine LUKACS; Evan RACHLIN; Paolo MARTINI; Stephen HOGE; Kerry BENENATO; Vlad PRESNYAK; Lei JIANG; Iain MCFADYEN; Ellalahewage Sathyajith KUMARASINGHE; Antonio FONTANELLAS ROMÁ; Pedro BERRAONDO LÓPEZ; Matías Antonio ÁVILA ZARAGOZÁ; Lin Tung GUEY; Staci SABNIS.
  • Applicants: ModernaTX Inc.; Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Acute intermittent porphyria.

WO2016097219

  • Title: Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease and other conditions.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; Rubén HERNÁNDEZ ALCOCEBA; Oihana MURILLO SAUCA.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Wilson's disease.

WO2016097218

  • Title: Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease and other conditions.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; Rubén HERNÁNDEZ ALCOCEBA; Oihana MURILLO SAUCA.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Rare diseases; Wilson's disease.

WO2021028299

  • Title: Viral particles for use in treating synucleinopathies such as Parkinson's diseases by gene therapy.
  • Inventors: Gloria GONZÁLEZ ASEGUINOLAZA; José Luis LANCIEGO PÉREZ; Ralph Michael LINDEN.
  • Applicants: Fundación para la Investigación Médica Aplicada; Consorcio Centro de Investigación Biomédica en Red del Área de Enfermedades Neurodegenerativas M.P., CIBERNED; Handl Therapeutics BV.
  • Indications: Central Nervous System; Parkinson's disease.

WO2021001377

  • Title: cPLA2e inducing agents and uses thereof.
  • Inventors: Ana María GARCÍA OSTA; María del Mar CUADRADO TEJEDOR; Marta PÉREZ GONZÁLEZ.
  • Applicants: Fundación para la Investigación Médica Aplicada; Universidad de Navarra.
  • Indications: Central Nervous System; Alzheimer's disease.

WO2016020307

  • Title: Novel compounds for use in cognition improvement.
  • Inventors: María del Mar CUADRADO TEJEDOR; Ana María GARCÍA OSTA; Julen OYARZABAL SANTAMARINA; María Obdulia RABAL GRACIA; Juan Antonio SÁNCHEZ ARIAS; Ana UGARTE BAZTÁN.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Central Nervous System; Alzheimer's disease.

WO2014131855

  • Title: Novel compounds as dual inhibitors of Phosphodiesterases and Histone Deacetylases.
  • Inventors: María del Mar CUADRADO TEJEDOR; Rafael FRANCO FERNÁNDEZ; Ana María GARCÍA OSTA; Julen OYARZABAL SANTAMARINA; María Obdulia RABAL GRACIA.
  • Applicants: Fundación para la Investigación Médica Aplicada.
  • Indications: Central Nervous System; Alzheimer's disease.

WO2014012964

  • Title: New antifibrinolytic compounds.
  • Inventors: Josune ORBE LOPATEGUI; Julen OYARZABAL SANTAMARINA; José Antonio PÁRAMO FERNÁNDEZ; José Antonio RODRÍGUEZ GARCÍA.
  • Applicants: Proyecto de Biomedicina CIMA S.L.
  • Indications: Cardiovascular; Hemorrhages.