Work with us
The Cima Universidad de Navarra is committed to the best professionals as a differentiating element and guarantor of this service. Its professionals come from different disciplines work at Cima: researchers, engineers, laboratory technicians, administrative and management personnel....
If you think that your educational and professional background may fit with any of the above-mentioned professional profiles or with any other of the Cima departments, do not hesitate to send us your curriculum vitae.
Lines of research
El grupo de Dinámica de la Respuesta Inmunitaria Antitumoral busca a un ayudante de laboratorio para unirse al grupo que se centra en el estudio de la función de las células dendríticas, los neutrófilos y endotelio vascular en su relación con los tumores, buscando nuevas estrategias de inmunoterapia frente al cáncer.
Descripción:
El Dr. Álvaro Teijeira es el Investigador Principal del grupo con amplia experiencia en inmunobiología e inmunología aplicada al cáncer, es experto en microscopía intravital y neutrófilos en cáncer que participa activamente en el desarrollo de los proyectos. Además de ser acreditado como investigador Ramón y Cajal.
El grupo “Dinámica de la Respuesta inmunitaria frente a tumores es un grupo de investigación emergente” especializado en el uso de técnicas de microscopía avanzada y video microscopía aplicadas al estudio de la inmunología tumoral e inmunoterapia, con expertise en neutrófilos y otras células mieloides.
Es un grupo que trabaja en sinergia con otros grupos del departamento de inmunoterapia, especialmente con los grupos dirigidos por los Drs Melero, Berraondo y Aranda.
Funciones específicas del puesto:
La persona a incorporarse se unirá al equipo para apoyar los proyectos en curso que estudian desde la inmunidad frente a las metástasis de hígado y el papel de los neutrófilos en la misma, al control de la infiltración de células inmunitarias por los vasos sanguíneos en los tumores.
El candidato tendrá tres funciones principales. Aproximadamente un tercio de su tiempo se dedicará a tareas técnicas de organización de laboratorio (manejo de colonias de ratones, manejo de pedidos, stocks y aparatajes,…) en conjunción con un equipo mayor. La mayor parte de su tiempo se dedicará al apoyo del trabajo del equipo en experimentos con animales, microscopía, citometría de flujo. Si el candidato/a presenta muy buena capacidad e interés podrá eventualmente ser responsable de proyectos independientes o de desarrollar nuevas técnicas y aplicaciones. Entre sus funciones se pueden incluir labores de formación a estudiantes de grado, máster o predoctorales.
Requisitos del candidato:
- Obligatorios:
- Grado superior en técnico de laboratorio, grado en biología, bioquímica o similar en ciencias de la vida o máster.
- Interés en incorporarse al grupo de forma estable.
- Complementarios:
- Experiencia en investigación, preferentemente en microscopía de fluorescencia,
manejo de animales, cultivo celular y citometría de flujo. Preferentemente en aeas de
inmunología u oncología.
- Certificación de manejo de animales de experimentación.
- Capacidad de entender textos y comunicarse en inglés.
Se ofrece:
- Contrato o beca hasta diciembre de 2025, con intención de prolongar otros dos años (sujeto a financiación).
- Remuneración según titulación y experiencia.
Se busca candidato/a predoctoral en el laboratorio de Ingeniería de Tejidos Cardíaca, Programa Ingeniería Biomédica del Cima Universidad de Navarra (Pamplona), para solicitar una Ayuda predoctoral FPU 2023 del Ministerio de Ciencia, Innovación y Universidades del Gobierno de España.
Se busca una persona creativa, dinámica y motivada. La persona seleccionada, formará parte de un ambiente altamente colaborativo, con la oportunidad de aplicar tecnologías de última generación en biofabricación, células madre y genómica en el campo de la medicina regenerativa. El desarrollo de la tesis doctoral, se realizará en colaboración con grupos internacionales de investigadores tanto básicos como clínicos.
Título del proyecto: Investigación de la miocardiopatía amiloide por transtiretina mediante modelos avanzados de enfermedad.
Descripción:
La cardiomiopatía amiloide por transtiretina (ATTR-CM) es una enfermedad causada por la producción anormal derivada del mal plegamiento de la proteína transtiretina por las células hepáticas, que posteriormente se libera sistémicamente y su depósito amiloide (agregación de láminas beta) en otros órganos tiene importantes implicaciones en la enfermedad.
En concreto, los agregados de estas fibrillas amiloides mal plegadas o mal ensambladas en el corazón están relacionados con la toxicidad cardiaca y la progresión hacia la insuficiencia cardiaca. Se presenta en dos formas: agregados de la forma natural de la proteína TTR que se encuentran aproximadamente en el 25% de las personas mayores de 80 años, mientras que la forma familiar se asocia a un fenotipo de cardiomiopatía más agresivo. En este caso concreto, la gran variabilidad genética hace que la evolución patológica sea extremadamente diferente. La falta de un conocimiento profundo sobre los mecanismos que conducen a la enfermedad da lugar a un mal pronóstico de los pacientes, con una supervivencia tras el diagnóstico actualmente en torno a los 5-15 años.
Se necesita una investigación intensiva, que incluya el desarrollo de nuevos modelos relevantes para la investigación de la enfermedad y el descubrimiento de tratamientos.
Codirectores del proyecto: Dra. Olalla Iglesias García y Dr. Juan José Gavira
Perfil deseado:
‐ Máster finalizado posterior a junio 2023 o en curso, con finalización en 2024
‐ Nota media del Grado / Licenciatura de 8 o superior (en una escala de 10). No se tendrán en cuenta solicitudes con un expediente menor a 8.
‐ Se valorará experiencia previa en investigación.
‐ Se valorará experiencia en Biología Celular y Molecular, experimentación animal, cultivo celular, modificación génica.
‐ Se valorarán conocimientos de secuenciación de RNA.
‐ Se requiere como mínimo un nivel B2 de inglés.
Enviar CV y expediente académico a: ogonmor@unav.es
Fecha límite: 1 de febrero de 2024, pero las solicitudes se evaluarán cuando se reciban.
We are searching for a highly motivated PhD that will be developing a 3-year fellowship in the Cima University of Navarra, funded by a prestigious grant from the National Institute of Health (NIH) and the Spanish Research Agency (AEI) within The Collaborative Research in Computational Neuroscience program (CRCNS). The project will be carried out in collaboration with groups from the Mayo Clinic, the University of Minnesota and the New York University
The candidate will lead a project directed to discover neurovascular disruptions in Alzheimer’s Disease using deep learning algorithms. The position will involve tissue processing and molecular techniques including single cell RNA-seq, spatial transcriptomics and data analysis. We seek motivated and ambitious candidates, with a Ph.D. or experience in either of the mentioned techniques. The role will have a strong load of bioinformatics, so experience in this field is required.
The position offers high-impact publication opportunities, attendance to international conferences, competitive salary, and excellent career development opportunities, including to work within an international consortium.
CIMA is highly reputed as one of the best Research Centers in Spain, located in Pamplona, a small city in Northern Spain, close to the border with France (Hendaye - 1h-, Bordeaux -2h-) and with beautiful sea cities in the Basque Country, such as San Sebastian -1h- and Bilbao -2h-. The facilities are first-in-class including animal husbandry, genomics unit - with two massive sequencers, single cell lib prep instruments, spatial transcriptomics-, confocal microscopy unit, to cite just a few.
Please submit CV, statement of interests and career goals. A zoom interview will be required during the selection process. An in-person visit to the center will also be possible for the selected candidates.
The fellowship will have a duration of 3 years. Funding (for the 3 years period): 121.274,22 €.
Contact:
Mikel Hernaez, PhD
Director, Computational Biology and Translational Genomics Program Head, Machine Learning for Biomedicine Lab
mhernaez@unav.es
Ana Garcia-Osta, PhD
Director, Gene Therapy for CNS Disorders Program agosta@unav.es
A fully funded CRIS Excellence postdoctoral position for 5 years is offered to join the research group led by Miguel F. Sanmamed MD, PhD at Cima and Clínica Universidad de Navarra at Pamplona, Spain.
We are looking for an enthusiastic and independent person to join our emerging lab with a special focus in cancer immunotherapy translational research. CRIS Excellence project focus on using our experience in immune-oncology, our expertise in hu-PDX models, our multiparametric single-cell technologies, and our translational infrastructure with a Cancer Center/Phase I Clinical trials Unit, to stablish a very complete translational research strategy, in which we will interrogate mechanism of action and effective immunotherapy combinations in preclinical models and patient-derived samples from patients treated with the same drugs. We expect this work will develop the biological rational to support the eventual design of more effective combinatorial treatment strategies in clinical trials to further advance cancer immunotherapy. The project is multidisciplinary and will involve the use of cell and molecular biology techniques, CRISPR/Cas9 genome editing, cytometry, tissue imaging and animal models.
The group will provide opportunities for interaction with other groups (internally, nationally and internationally) as well as industry partners.
Candidate’s requirements:
- PhD in biological or biomedical sciences.
- Background in Cancer Biology and/or Immunotherapy.
- Strong experience in flow cytometry, and other experimental tools in the research fields of immunology/molecular and cellular biology.
- Candidates with an international postdoc experience will be highly considered.
Interested applicants should send to msanmamed@unav.es a cover letter describing your previous research achievements and motivation to apply; your detailed CV including a list of publications and explaining your own contribution; contact information for at least two references.
The lab of Xabier Aranguren, Regenerative Medicine Program, at Cima University of Navarra, is seeking a highly motivated postdoc candidate to work on a research project focused on the molecular and epigenetic bases of human naïve iPS cells chimeric potential.
Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells. bioRxiv 2022.03.06.482812; doi: https://doi.org/10.1101/2022.03.06.482812
Funding
Offer within the framework of the BIOHEART project financed by the Government of Navarra. Project reference: 0011-1411-2022-000092
Job Information
- Application closing date: 31st July 2022.
-Employment start date: 1st of August 2022.
-Contract duration: 2 years and 5-month, with possibility of renovation.
Institution: Cima University of Navarra.
Background and project
Blastocyst complementation is a promising approach to generate organs in vivo from stem cells, using an animal recipient. The group has been working in this field for the last 8 years using mouse and rat animal models and cells, as well as human naïve iPS cells.
The project consists of the development of different strategies to increase human iPSC chimeric potential, and the generation of interspecific chimeras.
The selected candidate will have the opportunity to work in a young team in an excellent scientific environment and will have access to the state-of-the-art equipment and facilities dedicated to transgenesis. He/she will be trained for embryo microinjection.
Your Role:
Contribute to the project performing research to grasp the molecular and epigenetic bases of human naïve iPS cells chimeric potential by developing new strategies to increase cell contribution to interspecies chimerae.
Prepare papers for publication in leading international peer-reviewed journals.
Disseminate findings at conferences and meetings.
Your Profile:
- Holding a PhD diploma.
- A strong research track record in human iPS cells biology.
- Strong motivation.
- Ability to work both independently and as part of a team.
- Organization skills, initiative.
- Clarity in communication.
- Experience with gene editing technologies.
- Experience in transgenesis of mouse/pig models is desired but not required
- Spanish is not a requirement for English speakers.
What we offer:
- A position in a highly visible research project at the frontiers of knowledge in the field of stem cells and xenoorgan generation.
- A well-equipped work environment.
- Participation in courses and conferences.
- Comprehensive training in embryo micromanipulation.
Additional benefits:
- Accident insurance policy.
- Reduction on University training programs fees.
- Familiar allowance for children below 18 and for non-working partner.
- Free access to University sport facilities and library.
- Restaurant ticket, Transport ticket and Daycare ticket for tax discounts.
- Private health insurance policy “Poliza hospitalización platinum plus” from ACUNSA to all employees starting from the second year of contract. This policy can be voluntarily ampliated with discount to “Poliza Confort”. Employees’ children under 17 are given the “Poliza Confort” for free starting from the second year of contract. Discounts on insurance policy for employee spouse and children above 17 are offered.
The Institute is located at University of Navarra academic campus close to the center of the city with free bicycle and car parking lot.
Town: Pamplona is a highly dynamic and international city of Spain, which attracts a large number of university students and scientists. The city has plenty of bars and restaurants to enjoy the typical Navarra’s gastronomy and social life. The neighborhoods are the ideal destination for nature’s lovers, with woods of rare beauty. The Cantabric coast is 1h away.
Contact Information
Xabier Aranguren, Cima University of Navarra, 31008, Pamplona, Spain
Email: xlaranguren@unav.es
Please send your application including a motivation letter, your CV and reference letters from your previous employees.
The Foundation for Applied Medical Research, an entity owned by CIMA UNIVERSITY OF NAVARRA, will process the personal data provided for the purpose of managing and processing the request issued through this form. The basis for processing your data is the need to apply pre-contractual measures at the request of the interested party.
It is possible that we may communicate your data to other entities related to the University of Navarra interested in hiring people with your educational and professional profile. Unless you tell us otherwise, we will keep your data for a maximum of 3 years.
You can exercise your rights of access, rectification, deletion, opposition, and limitation of processing when you wish, among others that are included in our Data Protection Policy (information in Spanish), by sending an e-mail to the e-mail address dpocima@unav.es indicating in the title of the message: "CV sending form".