Work with us

En colaboración con la dirección de fundraising, contribuir al diseño y puesta en marcha del plan de captación de socios y fidelización con el fin de construir una sólida base social que apoye la investigación biomédica.

Tú misión será planificar, coordinar y ejecutar la estrategia de captación de socios, priorizando los canales de captación digital y de telemarketing. Además, diseñarás y ejecutarás las acciones de conversión, aumento de valor y fidelización de la base de colaboradores existente.

Se trata de una posición de nueva creación que requiere de orientación a resultados, gran capacidad de ejecución, flexibilidad y determinación para establecer los procesos y sistemas que contribuyan a establecer el plan de captación de socios y fidelización de la organización.

Funciones principales
•    Coordinar e implantar la estrategia de captación de socios en términos de objetivos, inversión, proveedores, difusión etc., con el fin de contribuir al cumplimiento de los objetivos y resultados de fidelización, retención y captación.
•    Diseñar, planificar y ejecutar las acciones de aumento de valor y conversión de la base de datos de colaboradores e interesados.
•    Garantizar el diseño, producción de contenidos y materiales de captación y fidelización (email marketing, briefing, argumentarios telefónicos, propuestas para donantes estratégicos, empresas…) para la adecuada fidelización, retención y captación (de socios, donantes, legatarios, etc.).
•    Definición e implementación de los diferentes flujos de comunicación con los colaboradores e interesados.
•    Participar en el diseño y redacción de contenidos que mejoren la vinculación y el grado de satisfacción de los colaboradores.
•    Establecer los procesos para garantizar la adecuada recogida de datos y gestión económica de las aportaciones de donantes y socios en CRM.
•    Elaborar informes para el adecuado seguimiento, análisis y evaluación de los objetivos y resultados con el fin de medir el retorno de las campañas activas, extraer aprendizajes e implementar mejoras que optimicen su rendimiento.
•    Hacer seguimiento del presupuesto de ingresos y gastos de su área.
•    Planificar la proyección de ingresos e inversión de las acciones de captación de socios.
•    Gestionar la relación con proveedores, validación de contenidos, elaboración de argumentarios y formación cuando así proceda.
•    Coordinarse con el Departamento de Comunicación para maximizar los esfuerzos de marketing y comunicación.
•    Coordinar los envíos a través de la plataforma de envío masivo, así como la gestión de respuestas y recogida de indicadores.
•    Tener capacidad para aplicar un pensamiento 360. Entender el user journey y todos los puntos por los que pasa el colaborador en la organización.
•    Estar al día y hacer seguimiento de otras iniciativas del sector para aportar ideas que mejoren el programa de captación y fidelización.

Requisitos específicos:
•    Titulación superior universitaria (preferiblemente en ciencias empresariales, económicas, marketing o similar).
•    Experiencia demostrada de al menos 5 años en el desarrollo e implementación de campañas de marketing, preferentemente digitales, dirigidas a la captación de clientes particulares en sectores de consumo o servicios, o de captación de socios y donantes particulares en organizaciones no lucrativas.

•    Experiencia y conocimiento de técnicas de reporte, métricas e indicadores clave (KPIs), y técnicas de gestión y control económico de proyectos.
•    Uso de CRM y plataformas de marketing automation, así como uso avanzado en el manejo de herramientas ofimáticas.
•    Experiencia en gestión con agencias y proveedores externos.
•    Proactividad, autonomía y orientación a resultados.
•    Capacidad de planificación y de gestión de proyectos.
•    Nivel alto de Excel.
•    Inglés hablado y escrito.

Adicionalmente se valorará:
•    Formación especializada en Marketing Digital.
•    Habilidades de redacción y copywriting.
•    Referencias.

Características del puesto:
•    Contrato indefinido.
•    Jornada semanal de 37,5 h. con flexibilidad horaria de entrada y salida y horario de verano.
•    Posibilidad de retribución flexible (guardería, seguro médico, transporte, ticket restaurante...)
•    Nivel salarial acorde a la experiencia profesional (27k€ - 30k€)
•    Lugar de trabajo: Pamplona.
•    Incorporación inmediata.

Cómo presentarse:
Las candidaturas deberán presentarse por email a cimapersonal@unav.es indicando la referencia “Técnico de captación de socios y fidelización” en el asunto del email.
•    Se incluirá CV y carta de motivación en un único documento de pdf.
 

La fecha límite para presentación de candidaturas es el 09/06/2023.
 

A postdoctoral position is offered at the OnTarget Group led by professor Silve Vicent at CIMA-University of Navarra (Erice et al, Clin Cancer Res 2023; Lasheras-Otero, J Inves Dermat 2022; Vallejo et al, J Hepatology 2021; Valencia et al, J Clin Invest 2020; Vallejo et al, Nat Comms 2017; Roman et al, Mol Cancer 2018; Roman et al, Cancer Res 2018). This is an industry-funded position to work on the characterization and molecular dissection of novel antitumor therapies in mutant KRAS-driven cancers.

The project will require, among other tasks: generation of new tumor models using the CRISPR/Cas9 technology, functional characterization of new elements within the KRAS network, testing of novel combinatorial therapies, and dissection of the mechanism of action for nominated genes and/or drug combinations using high-throughput (multiplex cytometry and IF, RNAseq, scRNAseq, proteomics and/or metabolomics) and focused approaches.  

We are looking for a self-motivated, resilient, autonomous person with team work and communication skills, and the ability to work in various projects. 

You should have, or (be about to obtain) a PhD in Cell Biology, Cancer Medicine, Immunology or other related discipline, with excellent research track record. Training in animal work will be a plus.  

You will be responsible for taking decisions regarding the project, obtaining data and planning future experiments. It is expected that you will be an innovative individual with an interest in applying your research skills to a challenging project, and willing to learn new techniques. 

You will also be expected to publish your results in a peer-reviewed journal. 

The post is for 1 year, renewable up to 3 years, and is expected to start on the 1st September 2023. 

Interested applicants should send a cover letter describing past experience and interests to: silvevicent@unav.es. Applications will be considered until June 30th (or until the position is filled). 

About CIMA:

CIMA is the biomedical research center of the Clínica Universidad de Navarra (https://cima.cun.es/en). Our scientific objective is to address current clinical problems and to propose the most effective treatment for each patient. CIMA is committed to excellence in translational research, based on novel biological knowledge and aimed at finding therapeutic solutions to patients' needs.  

We are a reference in cancer, immunotherapy, heart and liver diseases, and gene therapy research. With our academic status, we work on a non-profit basis to reinvest the surpluses in our research and to fulfill our mission of service to patients and society. To transfer the results of basic research to clinical application, CIMA’s Translation and Transfer unit establishes collaborations with biotechnology and pharmaceutical companies to facilitate the arrival of scientific discoveries to the bedside. 

A fully funded CRIS Excellence postdoctoral position for 5 years is offered to join the research group led by Miguel F. Sanmamed MD, PhD at Cima and Clínica Universidad de Navarra at Pamplona, Spain.

We are looking for an enthusiastic and independent person to join our emerging lab with a special focus in cancer immunotherapy translational research. CRIS Excellence project focus on using our experience in immune-oncology, our expertise in hu-PDX models, our multiparametric single-cell technologies, and our translational infrastructure with a Cancer Center/Phase I Clinical trials Unit, to stablish a very complete translational research strategy, in which we will interrogate mechanism of action and effective immunotherapy combinations in preclinical models and patient-derived samples from patients treated with the same drugs. We expect this work will develop the biological rational to support the eventual design of more effective combinatorial treatment strategies in clinical trials to further advance cancer immunotherapy. The project is multidisciplinary and will involve the use of cell and molecular biology techniques, CRISPR/Cas9 genome editing, cytometry, tissue imaging and animal models. 

The group will provide opportunities for interaction with other groups (internally, nationally and internationally) as well as industry partners.

Candidate’s requirements:
- PhD in biological or biomedical sciences. 
- Background in Cancer Biology and/or Immunotherapy.
- Strong experience in flow cytometry, and other experimental tools in the research fields of immunology/molecular and cellular biology.
- Candidates with an international postdoc experience will be highly considered. 

Interested applicants should send to msanmamed@unav.es a cover letter describing your previous research achievements and motivation to apply; your detailed CV including a list of publications and explaining your own contribution; contact information for at least two references.

Functions and tasks:

Bioinformatics analysis of multi-omics data generated in hematological translational research.

- Compare by BULK (exome and RNA sequencing) and single-cell (single-CELL RNAseq) omics techniques, the molecular signature of minimal residual disease cells that persist to treatment versus tumor molecules at diagnosis in a large series of patients with multiple myeloma in order to unveil the mechanisms of ultra-chemoresistance against two therapeutic standards.

- The proposed activities fall within the scope of HEALTH, focused on the analysis of the molecular signature of minimal residual disease in multiple myeloma.

Professional experience: 1 to 3 years

Requeriments:

University Degree in Biochemistry, Biology or Master's Degree in Bioinformatics or similar.

Working conditions: 

- Gross annual salary: 27.000€.

- Temporary contract for 12 months with the possibility of extending for another year, subject to availability of funds.

- Schedule: Monday to Friday (flexible schedule of entry and exit).

The person to be hired must meet the following requirements:

- To be equal or older than 16 and younger than 30 years old.

- To be registered as unemployed in the corresponding public employment service on the day prior to the start of the contract.

- To be registered in the National Register of Youth Guarantee.

- To be in possession of the required academic qualifications.

- Not having had a contractual relationship with the contracting entity or with associated or related companies (according to the definitions of these terms made in Annex 1 of Regulation (EU) number 651/2014) within 6 months immediately prior to the formalization of the contract.

This contract is under Resolution 18E/2023 of the Director General for Innovation, which approves the call for "Grants for the recruitment of research personnel. MRR Investigo 2023 Program, funded by the European Union-Next Generation EU.

Interested candidates must send their CV to: cimapersonal@unav.es, indicating in the subject of the email: Bioinformatician

Job Description:

It is necessary to hire a postdoctoral researcher, to work in the Cerebrovascular Diseases Network (RICORS), File RD21/0006/0008 - Cerebral Vascular Pathologies Network (Ictus), financed by the Instituto de Salud Carlos III with funds from the European Union - NextGeneration EU, which finance the actions of the Recovery and Resilience Mechanism (MRR).

His place of work will be the Cardiovascular Division at the Cima University of Navarra. He will be responsible for coordinating, designing and analyzing the experiments of the RICORS project of the Cima University of Navarra group, which has funding for the next years.

Functions:

Design and performance of cell culture assays and functional assays.
Biomolecular characterization of thrombi.
Characterization and transcriptomic analysis of extracellular vesicles.
Bioinformatics analysis, selection and validation studies of candidates.
Writing and presentation of results in English and Spanish.
Tasks
Processing, analysis and interpretation of clinical and experimental data.
Morphological/histological processing and analysis of thrombi and tissues.
Studies of cell activation and microvesicle release in cerebrovascular pathology.
Design and development of cytometric, molecular biology, and cellular techniques for the determination and characterization of extracellular vesicles.
Knowledge and development of experimental models of thrombosis will be an asset.

Working conditions of the offer:

- Working day: Full time (40 h per week).
- Duration: Fixed-term contract linked to programs financed with European Funds (NextGenerationEU/PRTR funds).
 

Publication date: 12/04/2023

Deadline: 11/05/2023 at 12:00h

More information (PDF)

Application process:

If you wish to submit your application to this selection process:

- Gather in a single PDF file all the information of your CV and alleged merits you wish to submit.
- Fill in the application form and attach the PDF file containing your application.

We seek a candidate to develop his Ph.D. in our Multiple Myeloma laboratory.

Project Title: Deciphering the cellular complexity of the human bone marrow microenvironment and its implication in the aging and pathogenesis of multiple myeloma.

Fortunately, today we have a great opportunity with the advent of single-cell sequencing technologies and computational tools that allow us to reveal the cellular composition and gene regulation in tissues with unprecedented resolution. Thus, this project aims to resolve the cellular heterogeneity and regulation of cells in the bone marrow (BM) microenvironment throughout aging and Multiple Myeloma (MM). These results will represent a unique opportunity for identifying mechanisms involved in the development and progression of MM from asymptomatic stages to clinically active MM.

All MM is preceded by an asymptomatic phase called monoclonal gammopathy of uncertain significance (MGUS). MM is a cancer of one type of BM cell, namely plasma cells, in which abnormal proliferation of these cells occurs, leading to multi-organ damage. Despite significant advances in treating MM patients, most eventually relapse and cannot be cured. The process of tumor formation and progression is influenced by its parenchymal composition, mesenchymal components, and the interconnection between them.

Therefore, to achieve our purpose, we will decipher the cellular composition and the changes occurring in the microenvironment of the human BM. We will study the effective cell-cell interactions of the diseased microenvironment and functionally validate the activation of these genes and pathways to determine whether they contribute to this disease and, therefore, can be used as prognostic markers and/or therapeutic targets for the treatment of these hematological pathologies.

Director: Dr. Isabel Calvo

Desired profile:

- Master's degree. Grade point average of 8 or higher (on a scale of 10).

- Previous research experience will be an asset. 

- Experience in Cell and Molecular Biology, animal experimentation, cell culture, and gene modification would be an asset. 

- Knowledge of Computational Biology is an asset.

- A minimum of B2 level of English is required. 

Send CV and academic transcript to:

Oscar González
ogonmor@unav.es
T + 34 948 194 700 ext 811047

Deadline: 15 May 2023, but applications will be evaluated as received.

We seek a candidate to pursue a Ph.D. in our Myeloid Pathology laboratory. A fellowship funds the position.

Project Title: Dissecting the Role of the Immuno-microenvironment in the Development of myelodysplastic syndromes.

Myelodysplastic syndromes (MDS) are aging-associated hematological malignancies that arise from expanding aberrant hematopoietic stem cell clones in the bone marrow (BM). MDS are genetically heterogeneous and incurable with available drug therapies, which cannot eradicate the aberrant cell clones. For this reason, we explored the possibility of intervening therapeutically in MDS at the early stages of the disease before aberrant cells overpopulate the BM and prognoses worsen irreparably.

The transcriptome of mononuclear BM cells from patients with clonal cytopenias of undetermined significance (CCUS) was characterized to identify the cellular and molecular alterations that occur with the onset of MDS. CCUS are precancerous MDS predecessor disorders occurring in elderly patients carrying MDS-causing mutations and thus represent an optimal setting to study the mechanisms leading to MDS development.

Our preliminary results suggest that cells of the innate immune system of patients with OSCC are transcriptionally reprogrammed towards an activated state but are terminally differentiated and functionally exhausted. Therefore, we propose to study the hypothesis that dysfunctions of the immune microenvironment in the early stages of MDS favor clonal expansion and disease progression, and therapeutic strategies that enhance the immune response in patients with OSCC or MDS could effectively prevent or halt disease onset. To this end, we will dissect the changes that occur in the immune microenvironment of patients with early stages of MDS:

Characterizing the microenvironment of MDS patients with low tumor burden (early stages) transcriptionally, immunophenotypically, and spatially in individual cells, including interactions between immune and non-immune cells.
Assessing the functionality of the immune cell repertoire in OSCC and MDS patients by analyzing their secretome and the cytokine-secreting and cytolytic capacities of the cells.
I will examine the feasibility of new-generation immune checkpoint inhibitor therapies targeting the immune response in MDS and identify and validate new therapeutic targets.
Director: Dr. Irene Gañan

Desired profile:

- Master's degree. Grade point average of 8 or higher (on a scale of 10).

- Previous research experience would be an asset. 

- Experience in Cell and Molecular Biology, animal experimentation, cell culture, gene modification would be an asset. 

- Knowledge of Computational Biology is an asset.

- A minimum of B2 level of English is required. 

Send CV and academic transcript to: 

Oscar González
ogonmor@unav.es
T + 34 948 194 700 ext 811047

Deadline: 15 May 2023, but applications will be evaluated as received.

We seek a candidate to pursue a Ph.D. in our Myeloid Pathology laboratory. The position is funded by a fellowship.

Project title: Study of the role of gene regulatory pathway alterations in myeloid pathology.

Myelodysplastic syndromes and acute myeloid leukemias are neoplasms in which there is an alteration in normal hematopoietic differentiation. Currently, the therapies available for treating these neoplasms are ineffective, which highlights the need for a deeper understanding of the molecular mechanisms that trigger aberrant hematopoietic differentiation in these patients, to design therapies that are specific and effective. So far, most studies have focused on genetic lesions, but transcriptional alterations still need further exploration.

In our group, using state-of-the-art NGS technologies, including single-cell analysis techniques, we aim to identify the gene regulatory pathways (transcription factors and target genes) altered in the malignant blood precursor cells of these patients. Given the reversible nature of such alterations, these regulatory pathways may represent potential therapeutic targets. Once characterized, we will use in vitro hematopoiesis models to identify, from among these pathways, those that are most relevant to the disease. In addition, we will study ways of attacking them with drugs, in isolation or in combination with conventional chemotherapy. Therefore, this project aims, through the use of novel technology, to identify key transcriptional alterations for these diseases, validate their biological role and determine whether they may represent potential therapeutic targets to improve the life expectancy of these patients.

Directors: Dr. Teresa Ezponda and Dr. Ana Alfonso.

Desired profile:

- Master's degree. Grade point average of 8 or higher, Bachelor's degree (on a scale of 10).

- Previous research experience will be an asset. 

- Experience in Cell and Molecular Biology, animal experimentation, cell culture, and gene modification would be an asset. 

- Knowledge of Computational Biology would be an asset.

- A minimum level of English B2 is required. 

Send CV and academic transcript to: 

Oscar González
ogonmor@unav.es
T + 34 948 194 700 ext 811047

Deadline: 15 May 2023, but applications will be evaluated as received.

We are looking for a PhD candidate in our Cancer Immunotherapy Lab, in CimaUniversidad de Navarra, Pamplona. The position is grant-funded. 
 

Project Title: Strategies of combined immutherapy of cancer based on intratumoral approaches. 

Combinations of immunotherapy are becoming the standard-of-care for many malignant diseases. 
In this project, mRNAs encoding immunostimulatory factors and immunostimulatory small molecules will be tested in mouse models via intratumoral administration.  

The strategy will be combined with systemic agents (i.e. anti-PD (1) and anti CD137). In depth immunological research will address the mechanisms of action. 

Director: Dr. Ignacio Melero. 

Desired profile:

- Master´s degree. 8 Grade-point average or higher (on a 10 scale).

- Previous research experience will be valued. 

- Experience in immunology, cancer immunology, animal experimentation, cell culture, confocal microscopy and gene-transfer will be valued. 

- B2 level of English is required at least. 

Sent CV to: eguirado@unav.es

Deadline: 1 June 2023, but applications will be evaluated when received. 

Within the framework of the 2021 Knowledge Generation R&D Projects, Project PID2021-124455OB-I00 financed by MCIN/ AEI /10.13039/501100011033/ and by FEDER A way of making Europe

Project title: "Impact of liver damage developed in Wilson's disease on the safety and efficacy of gene therapy and identification of the molecular mechanisms involved in copper liver pathology (CUTOX)"

Position offered: Bioinformatician

Responsible: Gloria González, Phd

Location of the Position: Laboratory of Gene Therapy for liver diseases of Cima

Functions:

The main functions of the person to hire will be:
Reanalyze the computer analysis of the RNAseq results obtained as a result of the evaluation of different experimental conditions both in cell cultures and in animal models within the framework of the mentioned project. Analysis of genetic modifications after gene editing using the CRISPR-Cas9 system.

Minimum Requirements:

The minimum requirements that the candidate must meet are:
Management of programming languages ​​(Python and MatLab), and knowledge of Statistical Methods
Advanced (Program: R), Treatment and Management of Experimental Data, Machine Learning, Data Mining.

It will be valued:

Other key issues for the selection are:
Intermediate-high knowledge of English, ability to work in a team.
Interested applicants should send their CV to the following email: ggasegui@unav.es

Dr. Aranguren’ lab is looking for enthusiastic and highly motivated candidates interested in developing a thesis project focused on the molecular and epigenetic bases of human naïve iPS cells chimeric potential.

Background and project 
Blastocyst complementation is a promising approach to generate organs in vivo from stem cells, using an animal recipient. The group works in this field using mouse, rat and human naïve iPS cells in mouse and pig animal models.

The project consists in the development of different strategies to increase human iPSC chimeric potential, and in the generation of interspecific chimeras.

The selected candidate will have the opportunity to work in a young team in an excellent scientific environment and will have access to the state-of-the-art equipment and facilities dedicated to transgenesis. He/she will be trained for embryo microinjection and human iPS culture and genetic engineering, between others.

Recent group’s publications related to the offer:
https://www.biorxiv.org/content/10.1101/2022.10.04.510637v1
https://pubmed.ncbi.nlm.nih.gov/36563688/
https://pubmed.ncbi.nlm.nih.gov/35883376/

Required profile:
•    University and master Degree in life or biomedical sciences
•    An academic record above 8.0

Contact Information:
• Xabier Aranguren, Cima University of Navarra, 31008, Pamplona, Spain
• Email: xlaranguren@unav.es 
•Website
• Please send your application including a motivation letter, your CV and reference letters from your previous employees. 

Purpose: In the framework of the R+D+i Projects in "strategic lines" CARTsol, Project PLEC2022-009217 funded by MCIN/AEI /10.13039/501100011033 and by the European Union NextGenerationEU/ PRTR, the recruitment of a Ph.D. is needed.
Functions: The main functions of the person to be hired will be:
- Design and generation of human CARs targeting breast cancer tumor antigens.
- Generation of CAR-T cells (human and murine) by lentiviral and retroviral transduction.
- Encapsulation of CAR-T cells in biodegradable porous capsules.
- In vitro studies to study the viability and effector functions of the encapsulated CAR-T cells.
- In vitro and in vivo pharmacokinetic studies to study the controlled release of CAR-T cells.
- Generation of orthotopic immunocompetent breast cancer and xenograft models to study the antitumor efficacy of encapsulated CAR-T cells.
- Adoptive cell therapy studies to study the antitumor efficacy of encapsulated CAR-T cells.
- Screening of adjuvant factors that through co-encapsulation with CAR-T cells enhance their antitumor action.
Minimum Requirements: 
- PhD in Molecular and Cellular Biology, Applied Medicine and Biomedicine, or similar.
- Solid experience in:
   - Cell culture 
   - Flow cytometry 
   - Molecular biology
   - Animal models of disease.
-Certificate and accreditation of competency to work with laboratory animals (rodents).
-Two letters of recommendation from thesis supervisors and/or postdoctoral positions.

Will be considered: 
-Proficiency in English
-Having published articles in scientific journals that certify having experience in the minimum requirements demanded.

Those interested should send their CV to the following e-mail address to mshervas@unav.es

Publication date: December 21st 2022

Purpose of the position: 
Performance of doctoral thesis in the cardiovascular diseases group.

Qualifications required:
Bachelor's and master's degree in the field of experimental and health sciences. 

Title of the project:
Identification of new molecular targets involved in the development of adverse cardiac remodeling and therapeutic application of anti-fibrotic nanoparticles.

Project director: Dr. Beatriz Pelacho

Number of positions offered: 1

Funding entity: FIMA

Required documentation: Updated curriculum vitae

Submission of applications and more information: bpelacho@unav.es

Application forms available at: https://www.unav.edu/investigacion/escuela-de-doctorado/financiacion-y-ayudas

Characteristics of the aid:
It will be in accordance with the provisions of the Convocatoria Marco de Ayudas Adscritas a Proyectos de Investigación para contratos predoctorales (Framework Call for Aid for Research Projects for pre-doctoral contracts).

Date of publication: November 30, 2022

The lab of Xabier Aranguren, Regenerative Medicine Program, at Cima University of Navarra, is seeking a highly motivated postdoc candidate to work on a research project focused on the molecular and epigenetic bases of human naïve iPS cells chimeric potential.
Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells. bioRxiv 2022.03.06.482812; doi: https://doi.org/10.1101/2022.03.06.482812

Funding

Offer within the framework of the BIOHEART project financed by the Government of Navarra. Project reference: 0011-1411-2022-000092
 

Job Information
- Application closing date: 31st July 2022.
-Employment start date: 1st of August 2022.
-Contract duration: 2 years and 5-month, with possibility of renovation.
Institution: Cima University of Navarra.
 

Background and project
Blastocyst complementation is a promising approach to generate organs in vivo from stem cells, using an animal recipient. The group has been working in this field for the last 8 years using mouse and rat animal models and cells, as well as human naïve iPS cells.
The project consists of the development of different strategies to increase human iPSC chimeric potential, and the generation of interspecific chimeras.
The selected candidate will have the opportunity to work in a young team in an excellent scientific environment and will have access to the state-of-the-art equipment and facilities dedicated to transgenesis. He/she will be trained for embryo microinjection.

Your Role:
Contribute to the project performing research to grasp the molecular and epigenetic bases of human naïve iPS cells chimeric potential by developing new strategies to increase cell contribution to interspecies chimerae.
Prepare papers for publication in leading international peer-reviewed journals.
Disseminate findings at conferences and meetings.

Your Profile:
- Holding a PhD diploma.
- A strong research track record in human iPS cells biology.
- Strong motivation.
- Ability to work both independently and as part of a team.
- Organization skills, initiative.
- Clarity in communication.
- Experience with gene editing technologies.
- Experience in transgenesis of mouse/pig models is desired but not required
- Spanish is not a requirement for English speakers.

What we offer:
- A position in a highly visible research project at the frontiers of knowledge in the field of stem cells and xenoorgan generation.
- A well-equipped work environment.
- Participation in courses and conferences.
- Comprehensive training in embryo micromanipulation.

Additional benefits:
- Accident insurance policy.
- Reduction on University training programs fees.
- Familiar allowance for children below 18 and for non-working partner.
- Free access to University sport facilities and library.
- Restaurant ticket, Transport ticket and Daycare ticket for tax discounts.
- Private health insurance policy “Poliza hospitalización platinum plus” from ACUNSA to all employees starting from the second year of contract. This policy can be voluntarily ampliated with discount to “Poliza Confort”. Employees’ children under 17 are given the “Poliza Confort” for free starting from the second year of contract. Discounts on insurance policy for employee spouse and children above 17 are offered.
 

The Institute is located at University of Navarra academic campus close to the center of the city with free bicycle and car parking lot.
 

Town: Pamplona is a highly dynamic and international city of Spain, which attracts a large number of university students and scientists. The city has plenty of bars and restaurants to enjoy the typical Navarra’s gastronomy and social life. The neighborhoods are the ideal destination for nature’s lovers, with woods of rare beauty. The Cantabric coast is 1h away.
 

Contact Information
Xabier Aranguren, Cima University of Navarra, 31008, Pamplona, Spain
Email: xlaranguren@unav.es

•Website

Please send your application including a motivation letter, your CV and reference letters from your previous employees.
 

We are seeking a highly motivated Computational scientist to join the Myeloma Research Laboratory at the Cima Universidad de Navarra. The selected candidate will join an international group of scientists that are leaders in the field of translational research in multiple myeloma and other hematological malignancies.

We offer a 3-year contract and a consolidated structure to achieve new outcomes in immunogenomics. The selected candidate will be working in a unique environment of a combined diagnostic and research laboratories. We have state-of-the-art technology and experimental models, together with large datasets of patients with multiomics and clinical data.
 

The successful candidate will: 
• Participate in the planning, processing, analysis and interpretation of multidimensional flow cytometry and next generation sequencing (RNA-seq, ChIP-seq, ATAC-seq, HI-C, single cell RNA-seq, etc.) data.
• Participate in the development of data analysis workflows and pipelines for high throughput “omics” data. 
• Collaborate in multiple projects and leadership in personal research projects.
• Implement and customize existing software tools for multiomic analysis. 
• Supervise and teach junior members of the lab.  
• Active participation in manuscripts, grants and abstracts.
Required qualifications:
• University degree and postgraduate training in computational biology & bioinformatics. 
• Experience in the data processing and statistical analysis of high-throughput data.
• Knowledge of informatics tools and visualization/data mining packages and an aptitude for optimally adapting them to specific problems.
• Knowledge of statistical programming environment (R/Bioconductor, Matlab) and programming languages (Perl, Python, Java…).
• Proficiency in written and spoken English.
• Good organizational, communication and interpersonal skills.
Desirable qualifications:
• PhD degree and postgraduate training in computational biology & bioinformatics.
• Familiarity with Linux/Unix environment and high-performance computing (clusters).
• Experience in interdisciplinary collaborations on bioinformatics services.
• Familiarity with contemporary basic biology and biomedical research topics.
Interested applicants should send a cover letter describing experience and interests as well as their CV including references to:
Bruno Paiva
bpaiva@unav.es
T + 34 948 194 700 ext 811038
 

Research group: The candidate will join the Laboratory of Atherothrombosis at the Program of Cardiovascular Diseases, a multidisciplinary research group including clinical and basic scientists. The group has an extensive experience in vascular pathologies and thrombosis, always combining clinical and basic research. The supervisor, Dr. Carmen Roncal, has contributed to more than 40 research articles, and the group has been involved in more than 30 national and international research projects. 

Research project: Peripheral artery disease (PAD) is one of the most prevalent cardiovascular (CV) condition globally with >200 million cases. Among PAD patients, those with concomitant diabetes mellitus progress faster, and more frequently advance to critical limb ischemia, boosting their risk of thrombosis, amputation and death (2 to 3-fold) compared to non-diabetic PAD subjects. Diabetes-induced endothelial dysfunction and platelet activation play a critical role in atherothrombosis, and thus the study of the molecular changes induced by hyperglycemia on those cell types might be useful to identify novel diagnosis and prognosis biomarkers in diabetic PAD patients. Nevertheless, the inaccessibility and diffuse nature of endothelial cells hinders the possibility of studying them. In this regard, Extracellular vesicles (EVs), nanometric lipidic spheres released into blood by most cell types carrying nucleic acids, proteins and lipids from parental cells, offer a unique opportunity to analyse the content of parental cells in the bloodstream. 

The aim of this translational projects is to identify endothelial and platelet associated molecular patterns in diabetic PAD patients that will provide novel CV risk biomarkers and therapeutic targets for this high cardiovascular risk subgroup. To address our purpose, we will isolate and sequence endothelial and platelet derived EVs from diabetic and non-diabetic PAD patient, select 3 to 5 differentially expressed genes, and measure their blood levels to determine their association with worse outcome in PAD (diabetic and non-diabetic) patients. The regulation of the selected candidates by hyperglycemia will be studied in vitro and in vivo in endothelial cells, and mice models of diabetes and atherosclerosis. Finally, machine learning methods will be applied to calculate algorithms that might further improve the diagnosis and risk stratification of diabetic PAD patients.

Candidate description: We look for a highly motivated Master degree candidate, with excellent records, who is expected to enroll in a PhD programme at the Universidad de Navarra and to apply for PhD funding.

The candidate will join a research group focused in translational studies, that benefits from the experience of clinicians as well as molecular and cellular biologist with broad experience in the physiopathology of atherosclerosis and thrombosis. The candidate will receive training in cellular and molecular biology, always maintaining the focus on the translation nature of the project. He/she will participate in weekly laboratory meetings, and the advances of the project will be presented in lab seminars and national and international congresses. The candidate will be encouraged for a short-term stage abroad.

A bachelor and a master in Biomedical Sciences (e.g. biology, biochemistry, pharmacy, medicine, biomedicine…) is required. The fellow must be fluent in English (both oral and written). Previous experience in histology, cellular and molecular biology, and statistics is recommended but not essential.

Interested applicants should send a cover letter describing past experience and interests as well as their CV to: Carmen Roncal Mancho, croncalm@unav.es

A postdoctoral position supported by “la Caixa Research” is available in the group headed by Maite Huarte at Cima Universidad de Navarra, in Pamplona, Spain.

• The candidate will work on a collaborative project with a multidisciplinary team of molecular, structural, computational and biophysics experts to understand the role of lncRNAs in the response to replicative stress in cancer cells.
• We are looking for highly motivated and talented individuals, preferentially with previous expertise in molecular, RNA, chromatin and cancer biology.
• Knowledge of the analysis and interpretation of genomic data are desirable.

The position offers the opportunity for professional growth by working in an interactive and dynamic international environment of translational and basic science research.
 

Interested applicants should send a cover letter describing their past experience and interests, as well as their CV (including Educational Information and scores as well as references) to: Maite Huarte, maitehuarte@unav.es. T + 34 948 194 700 ext 814000

A PhD position supported by “Agencia Estatal de Investigación” will open soon to work in the group headed by Maite Huarte at Cima Universidad de Navarra, in Pamplona, Spain.
Our lab aims to understand how RNA in general and lncRNA in particular affect chromatin replication and gene regulation in cancer. By working in a stimulating environment with an international team of translational and basic researchers, the position offers the opportunity of being trained in the latest technologies for the study of non-coding genes, ranging from molecular and cellular biology to epigenetics and functional genomics.
Please visit our lab webpage.

• We are looking for candidates with an interest in applying to this PhD call, likely to open sometime after the summer, bearing in mind that the call will impose formal requirement for applicants. Salaries and other conditions will be defined.
• We look for highly motivated individuals with a science/master’s degree.
• Some experience in molecular and cellular biology is highly recommended and background in biology positively valued.
• Excellent knowledge of the English language is required.

Interested applicants should send a cover letter describing their past experience and interests as well as their CV (including Educational Information and scores as well as references) to: Maite Huarte, maitehuarte@unav.es. T + 34 948 194 700 ext 814000