Dr. Miguel Fernández de Sanmamed

Principal Investigator of the Applied and Translational Onco-Immunology group.
Primary focus on cancer immunotherapy, with particular attention to skin and lung cancer, humanized PDX models, and new circulating biomarkers

Be part of: Cima Universidad de Navarra Clínica Universidad de Navarra Cancer Center Clínica Universidad de Navarra

INDEX H 47

Professional career

Staff physician in the Department of Medical Oncology at Clínica Universidad de Navarra. Principal Investigator in the Immunology and Immunotherapy Program at Cima Universidad de Navarra since 2018.

Training in CyTOF (exposure) at Stanford University, USA (2014).

Postdoctoral training in the Immunobiology Program at Yale University (USA) from 2013 to 2018.

Postdoctoral training at the University of Navarra under a Río Ortega contract (2011–2013).

He completed specialty training in Medical Oncology at Hospital Universitario Central de Asturias (Oviedo), 2010.

Medical degree (2005) from the University of Santiago de Compostela and PhD in Medicine (2011) from the University of Oviedo.

RESEARCH AREAS

2023: Highly Cited Researcher by Web of Science Group (Clarivate).
2023–Present: CRIS Excellence Program. CRIS Contra el Cáncer
2022: imCORE Early Career Networking. imFLAME researcher award.
2021–Present: Spanish Association Against Cancer. LAB AECC.
2020–2022: Spanish Association Against Cancer. Junior Clinical (Mentor)
2019–Present: Government of Spain. Ministry of Education. FIS.
2018–Present: Government of Spain. Ministry of Education. Miguel Servet Contract.
2018–2019: Spanish Society of Medical Oncology. Return Grant.
2016: European Society for Medical Oncology (ESMO). Travel award to the annual meeting.
2016: SITC and Astra Zeneca. Clinical Fellowship in Cancer Immunotherapy in NSCLC.
2013–2015: Spanish Society of Medical Oncology. Translational research grant
2011–2013: Government of Spain. Ministry of Education. Río Hortega Translational Research Fellowship.
2011: Annual Meeting of the Spanish Society of Medical Oncology. Award for Best Oral Presentation

AREAS OF INTEREST

Cancer immunotherapy, with particular attention to skin cancer and lung cancer (interleukin 8, T-cell activators, bispecific mAbs).
Humanized PDX models (model optimization, application to investigate new therapies targeting Tregs, implementation of inflamed models with T cells and without T cells)
New circulating biomarkers (exosomes, anti-drug antibodies)

Activity

In teaching

2019–Present: Assistant Professor. Faculty of Medicine, University of Navarra.
2018–Present: Assistant Adjunct Professor. Department of Oncology. Yale School of Medicine.
2021–2022: Supervisor of the Master’s Thesis of Cyril Puyo Uriarte. «The LILRB2/HLA-G pathway as a novel target in cancer immunotherapy». University of Navarra, Spain. Academic year: 2021–2022
2020–2021: Co-supervisor of the Master’s Thesis of José Mario Rojas Morales. «Anti-drug antibodies (ADA) as a mechanism of resistance in cancer immunotherapy». University of Navarra, Spain. Academic year: 2020–2021
2019–2020: Co-supervisor of the Master’s Thesis of María Romay Egurrechea. «Identification of tumor exosomes as an analysis tool in a humanized PDX model». University of Navarra, Spain. Academic year: 2019–2020
2018–2019: Supervisor of the Master’s Final Project of Inmaculada Aguilera Buenosvinos. «Alternative hu-PBMC/Immunoavatar mouse models for the study of cancer immunotherapies with minimal graft-versus-host disease». University of Navarra, Spain. Academic year: 2018–2019.
2016: Co-supervision of Omar Carranza’s thesis. Doctoral student. Project: «Serum Interleukin-8 reflects tumor burden and response to treatment in neoplasms of multiple tissue origins». University of Navarra, Spain. Highest degree.
2015–2016: Assistant in the Department of Immunobiology. Yale University.
2010–2013: Assistant in the Department of Immunology. University of Navarra
2009–2011: Assistant in the Department of Internal Medicine. University of Oviedo

In research

Author of more than 90 articles published in international scientific journals.
Contributor to more than 5 book chapters in the specialty.

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Scientific Institutions

Member of the Board of Directors of ASEICA.
ESMO Faculty Member for the Translational Research.

Scientific Institutions

2016 | European Society of Medical Oncology (ESMO). Annual Meeting Travel Award.
2011 | Spanish Society of Medical Oncology Annual Meeting. Best Oral Communication Award.