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Dr. Irene Ganan-Gomez

Principal investigator of the Myelodysplastic Neoplasia group.
Preferred dedication: Translational research on the pathogenic mechanisms driving the onset and progression of myelodysplastic syndromes

Be part of: Cima Universidad de Navarra Cancer Center Clínica Universidad de Navarra
INDEX H 15

Professional career

  • Pharmacy Degree, Universidad de Alcalá (Madrid, Spain), 2008
  • Master’s Degree in Cell Signaling and Therapeutic Targets, Universidad de Alcalá (Madrid, Spain), 2009
  • PhD, Universidad de Alcalá (Madrid, Spain), 2013
  • Postdoctoral Fellowship, Department of Leukemia, The University of Texas MD Anderson Cancer Center, 2014-2019
  • Instructor (Research Faculty Appointment), Department of Leukemia, The University of Texas MD Anderson Cancer Center, 2019-2023
  • Investigator (Myelodysplastic Neoplasia group), Cancer Center Clínica Universidad de Navarra (Pamplona, Spain), 2023-present

RESEARCH AREAS

  • Introduction to Research Activity Award (UAH, 2009) 
  • Research Staff Training Award (Council of Science and Technology, Castilla-La Mancha, Spain, 2009-2013)
  • Jose Castillejo Travel Awards (Council of Science and Technology, Castilla-La Mancha, Spain, 2010, 2011) 
  • Kimberly Patterson Fellowship in Leukemia Research Award (MDACC Endowed Fellowship Award Program, 2016) 
  • Career Enhancement Award (MDACC Leukemia SPORE Program, 2019-2020) 
  • Marie Sklodowska-Curie Actions Postdoctoral Fellowship 2022 (European Research Agency, September 2023-December 2023)
  • AECC Investigator Award 2022 (Asociación Española Contra el Cáncer, declined owing to incompatibility) 
  • Ramón y Cajal Award 2022 (Agencia Española de Investigación, September 2024-August 2029)
  • Senior Talent Andía Award 2023 (Gobierno de Navarra, December 2023-December 2028) 

AREAS OF INTEREST

Dr. Gañán Gómez’s research is aimed at identifying novel therapeutic targets for MDS patients in all disease stages, with a particular interest in unravelling the cell evasion mechanisms that enable MDS development and progression and the hierarchy-specific vulnerabilities sustaining the survival and expansion of MDS HSCs.

  • Mechanisms of immune evasion in low-risk MDS
  • Hematopoietic hierarchy-dependent oncogenic dependencies of MDS stem cells 

Activity

In teaching

Dr. Gañán Gómez is co-directing the Doctoral Thesis entitled “Dissecting the Role of the Immune Microenvironment in the Onset of Myelodysplastic Syndromes”. 

In research

Overall, Dr. Gañán Gómez’ scientific production has been published in high-impact journals (6 first-authored papers in Q1), widely cited (over 1500 total citations; h-index=15) and of high translational impact in biomedicine. In addition, along her career she has participated in a number of transfer-of-knowledge and service activities, sharing her expertise in HSC biology techniques with the scientific community in invited seminars and publications, participating in the training of multiple students and serving as a thesis evaluator for the international certification of a PhD candidate (Belen Sánchez Gómez, UAH, 2022). She is also a scientific manuscript reviewer for several Q1 journals and a member of the Spanish Group of Myelodysplastic Syndromes (GESMD).
More information

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