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Dr. Irene Ganan-Gomez

Principal investigator of the Myelodysplastic Neoplasia group.
Preferred dedication: Translational research on the pathogenic mechanisms driving the onset and progression of myelodysplastic syndromes

Be part of: Cima Universidad de Navarra Cancer Center Clínica Universidad de Navarra
INDEX H 15

Professional career

  • Pharmacy Degree, Universidad de Alcalá (Madrid, Spain), 2008
  • Master’s Degree in Cell Signaling and Therapeutic Targets, Universidad de Alcalá (Madrid, Spain), 2009
  • PhD, Universidad de Alcalá (Madrid, Spain), 2013
  • Postdoctoral Fellowship, Department of Leukemia, The University of Texas MD Anderson Cancer Center, 2014-2019
  • Instructor (Research Faculty Appointment), Department of Leukemia, The University of Texas MD Anderson Cancer Center, 2019-2023
  • Investigator (Myelodysplastic Neoplasia group), Cancer Center Clínica Universidad de Navarra (Pamplona, Spain), 2023-present

RESEARCH AREAS

  • Introduction to Research Activity Award (UAH, 2009) 
  • Research Staff Training Award (Council of Science and Technology, Castilla-La Mancha, Spain, 2009-2013)
  • Jose Castillejo Travel Awards (Council of Science and Technology, Castilla-La Mancha, Spain, 2010, 2011) 
  • Kimberly Patterson Fellowship in Leukemia Research Award (MDACC Endowed Fellowship Award Program, 2016) 
  • Career Enhancement Award (MDACC Leukemia SPORE Program, 2019-2020) 
  • Marie Sklodowska-Curie Actions Postdoctoral Fellowship 2022 (European Research Agency, September 2023-December 2023)
  • AECC Investigator Award 2022 (Asociación Española Contra el Cáncer, declined owing to incompatibility) 
  • Ramón y Cajal Award 2022 (Agencia Española de Investigación, September 2024-August 2029)
  • Senior Talent Andía Award 2023 (Gobierno de Navarra, December 2023-December 2028) 

AREAS OF INTEREST

Dr. Gañán Gómez’s research is aimed at identifying novel therapeutic targets for MDS patients in all disease stages, with a particular interest in unravelling the cell evasion mechanisms that enable MDS development and progression and the hierarchy-specific vulnerabilities sustaining the survival and expansion of MDS HSCs.

  • Mechanisms of immune evasion in low-risk MDS
  • Hematopoietic hierarchy-dependent oncogenic dependencies of MDS stem cells 

Activity

As an educator

Dr. Gañán Gómez is co-directing the Doctoral Thesis entitled “Dissecting the Role of the Immune Microenvironment in the Onset of Myelodysplastic Syndromes”. 

As a researcher

Overall, Dr. Gañán Gómez’ scientific production has been published in high-impact journals (6 first-authored papers in Q1), widely cited (over 1500 total citations; h-index=15) and of high translational impact in biomedicine. In addition, along her career she has participated in a number of transfer-of-knowledge and service activities, sharing her expertise in HSC biology techniques with the scientific community in invited seminars and publications, participating in the training of multiple students and serving as a thesis evaluator for the international certification of a PhD candidate (Belen Sánchez Gómez, UAH, 2022). She is also a scientific manuscript reviewer for several Q1 journals and a member of the Spanish Group of Myelodysplastic Syndromes (GESMD).
More information

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