LKB1: Controlling Quiescence and Genomic Integrity at Home

01-oct-2018 | Revista: Trends in Endocrinology & Metabolism

Carmen Berasain, Matías A Ávila

Abstract

The pleiotropic liver kinase B1 (LKB1) controls metabolism, cell polarity, and proliferation in an apparently cell- and context-specific manner. A recent study in Cell Reports has demonstrated that LKB1 is essential to maintain the characteristic quiescence of the liver and to secure genomic integrity during liver regeneration independently of AMPK

CITA DEL ARTÍCULO Trends Endocrinol Metab. 2018 Oct;29(10):668-670. doi: 10.1016/j.tem.2018.03.017. Epub 2018 Apr 5.

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Nuestros autores

Dra. Carmen Berasain Lasarte Ver Curriculum

Investigadora | Investigadora principal Grupo de Investigación en Hepatología: Carcinogénesis (HEPACAN)

Dr. Matías Ávila Zaragozá Ver Curriculum

Investigador | Investigador principal Hepatología: Metabolismo, epigenética y cáncer hepático