Amyotrophic lateral sclerosis research
Amyotrophic lateral sclerosis, or ALS, is a neurodegenerative disease that occurs when motor neurons (or motor neurons), nerve cells responsible for controlling the movement of voluntary muscles, die or progressively degenerate. This gradually causes muscle weakness and atrophy, spasms or cramps. As it progresses, it can also lead to difficulty in speaking, swallowing or breathing normally. Although the causes are still unknown, in some cases they are genetic.
This disease is also known as Lou Gehrig's disease. It currently has no cure and affects approximately 5 out of every 100,000 people worldwide.
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We dream of curing amyotrophic lateral sclerosis
Treatment options have increased significantly in recent years, but much remains to be discovered.
We deepen our knowledge of the mechanisms that determine the survival of motor neurons.
We look for diagnostic biomarkers of the disease and design possible new treatments.
We work closely with researchers and clinicians to rapidly translate discoveries from the laboratory to the patient.
REFERENCES IN TRANSLATIONAL RESEARCH
Parkinson's Disease Research Group
Reference team in preclinical research in Parkinson's disease and other movement disorders. This group has a research line that studies the cellular and molecular mechanisms associated with neurodegeneration in ALS and other neurodegenerative diseases.
It is part of the Gene Therapy of Neurological Diseases Program.