Research projects
Cima Universidad de Navarra
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Cancer gene therapyActive
Colorectal cancer therapy based on optimized immune checkpoint inhibitors using self-replicating RNA
Cima Principal Investigator: Cristian Smerdou PicazoFunder: Instituto de Salud Carlos IIIAward year 2022 -
Therapeutic Genes for Neurodegenerative DiseasesActive
CRCNS: Deep Learning to Discover Neurovascular Disruptions in Alzheimer's Disease
Cima Principal Investigator: Ana Mª García OstaFunder: Instituto de Salud Carlos IIIAward year 2023 -
AptamerActive
Selective blockade of the IL6/STAT3/SMG1 pathway in multiresistant circulating tumor cells (CTCs) as a pathway of sensitization to oncoimmunotherapy
Cima Principal Investigator: Fernando Pastor RodríguezFunder: Instituto de Salud Carlos IIIAward year 2023 -
Therapeutic long non-coding RNAs and integrated stress in CancerActive
Rational to modulate the Microbiome-induced Endoplasmic Reticulum stress as tool to avoid the immune evasion in Hepatocellular Carcinoma (RETO)
Cima Principal Investigator: Josepmaría ArgemíFunder: Instituto de Salud Carlos III -
DNA and RNA MedicineActive
MCI PID2022-137327OA-I00 IntegrAAV
Cima Principal Investigator: Carmen UnzuFunder: Ministerio de Ciencia, Innovación y Universidades -
Translational OncologyActive
The innate immune system as a therapeutic target in lung tumors resistant to immunotherapy based on PD-1/PD-L1 blockade
Cima Principal Investigators: Rubén Pío Osés, Daniel Ajona Martínez-PoloFunder: Instituto de Salud Carlos IIIAward year 2023 -
Hepatology: Carcinogenesis (HEPACAN)Active
PID2022-137181OB-I00 Characterization of SLU7 proteome and interactome and their rewiring in carcinogenesis: from epigenetics to protein stability (SLUTOME)
Cima Principal Investigator: Carmen Berasain LasarteFunder: Instituto de Salud Carlos III -
Vaccine DevelopmentActive
Combination immunotherapies against hepatocarcinoma: modulation of the lymphoid and myeloid compartments
Cima Principal Investigator: Pablo Sarobe UgarrizaFunder: Instituto de Salud Carlos IIIAward year 2024 -
AptamerActive
Boosting abscopal effect and minimizing locoregional failure by blockade of IL6/STAT3/SMG1 axis in onco-radiotherapy
Cima Principal Investigator: Fernando Pastor RodríguezFunder: Asociación Española contra el CáncerAward year 2023 -
Adoptive Cell TherapyCompleted
HLA-expressing transgenic mice to identify tumor-specific TCRs for cancer treatment: Application to Hepatocarcinoma
Cima Principal Investigator: Sandra Hervás StubbsFunder: Instituto de Salud Carlos III