SOCRATHeS: Development of innovative CAR-T Therapies for the Treatment of Hematological and Solid Tumors

Project information

The SOCRATHeS project aims to advance the development of a critical technological platform for implementing CAR-T cell-based antitumor therapies in Navarra.
CAR-T cell-based antitumor therapies in Navarra.

The results of the previous strategic project (the DESCARTHeS project) have allowed the development of several candidates to advance toward clinical trials for treating acute myeloid leukemia (AML) or hepatocarcinoma, cholangiocarcinoma, or pancreatic cancer. Thus, one objective of this project will be to continue advancing these candidates towards the clinic, carrying out an exhaustive study to rule out toxicities and confirm their efficacy in relevant tumor models. In turn, this project aims to establish a platform to facilitate the future development of new CAR-Ts for other hematological malignancies and gastrointestinal cancers.

• Convocation: PROYECTOS ESTRATEGICOS DE I+D 2022-2025 DEL GOBIERNO DE NAVARRA
• Reference: 0011-1411- 2022-000088
• Start date: May 1, 2022
• End date: December 31, 2024
• Funder: Gobierno de Navarra
• Nature of project: Regional
• Award year 2022