Scientific publications

Consolidating Radiotherapy with Immunotherapy. Scientific Publication

Oct 15, 2021 | Magazine: Clinical Cancer Research

Maria E Rodriguez-Ruiz  1   2   3 , Miguel F Sanmamed  1   2   3 , Irantzu Serrano-Mendioroz  1   2 , Ignacio Melero  4   2   3   5

Abstract

Radiotherapy and immunotherapy can be concomitantly or sequentially combined seeking synergistic effects in terms of control of irradiated tumors and abscopal effects on nonirradiated lesions.

Clinical-trial testing of such combinations faces several obstacles to demonstrate efficacy and needs improvements in trial design, patient selection, evaluation of results and biomarker discovery. See related article by Foster et al., p. 5510.

CITATION Clin Cancer Res. 2021 Oct 15;27(20):5443-5445. doi: 10.1158/1078-0432.CCR-21-2335. Epub 2021 Aug 3

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Our authors

Imagen de la Dra. Esperanza Rodríguez Ruiz, especialista en oncología radioterápica de la Clínica Universidad de Navarra
Dr. María Rodríguez Ruiz [SP] Curriculum
Clinical Researcher Immunology and Immunotherapy Research Program
Imagen del Dr. Miguel Fernández de Sanmamed Gutiérrez, Investigador principal del grupo Onco-Inmunología Aplicada y Traslacional de la Clínica Universidad de Navarra
Dr. Miguel Fernández de Sanmamed Gutiérrez Curriculum
Researcher | Principal Investigator Applied and Translational Onco-Immunology Research Group
Imagen del Dr. Ignacio Melero Bermejo, especialista en Inmunología de la Clínica Universidad de Navarra.
Dr. Ignacio Melero Bermejo Curriculum
Researcher | Principal Investigator Combination Strategies for Translational Immunotherapy Research Group
Irantzu Serrano Mendioroz
Laboratory technician Combination Strategies for Translational Immunotherapy Research Group