Scientific publications
For Whom the Cell Tolls? Intratumoral Treatment Links Innate and Adaptive Immunity. Scientific Publication
Feb 15, 2019
| Magazine: Clinical Cancer Research
Ivan Marquez-Rodas, María Angela Aznar, Antonio Calles, Ignacio Melero
Abstract
Intratumoral immunotherapy can potentially modulate the tumor microenvironment (TME) and potentiate the effects of concomitant or sequential systemic immunotherapies. Intratumoral administration of different Toll-like receptor agonists, including TLR4, can potentiate these effects through innate and adaptive immunity connection.
CITATION Clin Cancer Res. 2019 Feb 15;25(4):1127-1129. doi: 10.1158/1078-0432.CCR-18-2690. Epub 2018 Sep 27.
Our authors
Senior Researcher | Principal Investigator
Immunology and Immunotherapy Research Program