Scientific publications
- [COMBINATION STRATEGIES FOR TRANSLATIONAL IMMUNOTHERAPY]
- [CANCER DIVISION]
- [IMMUNOLOGY AND IMMUNOTHERAPY]
- [CYTOKINE-BASED THERAPEUTICS]
Druggable targets in cytokine release syndromes. Scientific Publication
Sep 1, 2023
| Magazine: Clinical Cancer Research
Carlos Luri-Rey 1 , Iñaki Eguren-Santamaria 2 , Ignacio Matos 3 , Pedro Berraondo 4 , Ignacio Melero 5
Abstract
Bispecific T-cell engagers and CAR T-cells share the problem of eliciting acute systemic inflammation episodes known as Cytokine Release Syndrome (CRS).
Knowledge on the sequential waves of cytokines that can be neutralized with clinically available agents is crucial to prevent or treat this condition without jeopardizing the antitumor therapeutic outcome.
CITATION Clin Cancer Res. 2023 Sep 1. doi: 10.1158/1078-0432.CCR-23-1975

Our authors

Carlos Luri Rey
Researcher | Principal Investigator
Cytokine-Based Therapeutics Research Group
Researcher | Principal Investigator
Combination Strategies for Translational Immunotherapy Research Group