Scientific publications
Cima Universidad de Navarra
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G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models
June 1, 2022 | Magazine: Biomedicine & PharmacotherapyFilipa Moreira-Silva 1, Gonçalo Outeiro-Pinho 2, João Lobo 3, Rita Guimarães 4, Vítor M Gaspar 5, João F Mano 6, Xabier Agirre 7, António Pineda-Lucena 8, Felipe Prosper 9, Jesus M Paramio 10, Rui Henrique 11, Margareta P Correia 12, Carmen Jerónimo 13
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- [THERAPEUTIC INNOVATION]
- [SOLID TUMOR]
- [HEMATO-ONCOLOGY]
- [HEPATOLOGY: METABOLISM, EPIGENETICS AND CARCINOGENESIS]
- [HEPATOLOGY: MOLECULAR MECHANISMS AND TARGETS IN LIVER CARCINOGENESIS]
New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
May 26, 2022 | Magazine: Journal of Experimental & Clinical Cancer ResearchLeticia Colyn # 1 , Gloria Alvarez-Sola # 1 2 , M Ujue Latasa # 1 3 , Iker Uriarte 1 2 , Jose M Herranz 1 2 , Maria Arechederra 1 2 3 , George Vlachogiannis 4 , Colin Rae 5 , Antonio Pineda-Lucena 6 , Andrea Casadei-Gardini 7 , Federica Pedica 8 , Luca Aldrighetti 9 , Angeles López-López 10 , Angeles López-Gonzálvez 10 , Coral Barbas 10 , Sergio Ciordia 11 , Sebastiaan M Van Liempd 12 , Juan M Falcón-Pérez 2 12 13 , Jesus Urman 3 14 , Bruno Sangro 2 3 15 , Silve Vicent 3 16 17 , Maria J Iraburu 18 , Felipe Prosper 19 , Leonard J Nelson 20 , Jesus M Banales 2 18 21 , Maria Luz Martinez-Chantar 2 22 , Jose J G Marin 2 23 , Chiara Braconi 5 24 , Christian Trautwein 25 , Fernando J Corrales 2 11 , F Javier Cubero 2 26 , Carmen Berasain # 1 2 3 , Maite G Fernandez-Barrena # 1 2 3 , Matias A Avila # 27 28 29
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- [HEPATOLOGY: METABOLISM, EPIGENETICS AND CARCINOGENESIS]
- [HEMATO-ONCOLOGY]
- [TRANSLATIONAL IMMUNOMICS IN HEMATOLOGICAL NEOPLASMS]
- [THERAPEUTIC INNOVATION]
- [HEPATOLOGY: MOLECULAR MECHANISMS AND TARGETS IN LIVER CARCINOGENESIS]
Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
January 4, 2019 | Magazine: HepatologyMarina Bárcena-Varela, Stefano Caruso, Susana Llerena, Gloria Álvarez-Sola, Iker Uriarte, M Ujue Latasa, Raquel Urtasun, Sandra Rebouissou, Laura Alvarez, Maddalen Jimenez, Eva Santamaría, Carlos Rodriguez-Ortigosa, Giuseppe Mazza, Krista Rombouts, Edurne San José-Eneriz, Obdulia Rabal, Xabier Agirre, Maria Iraburu, Alvaro Santos-Laso, Jesus M Banales, Jessica Zucman-Rossi, Felipe Prósper, Julen Oyarzabal, Carmen Berasain, Matías A Ávila, Maite G Fernández-Barrena
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- [THERAPEUTIC INNOVATION]
- [HEMATO-ONCOLOGY]
- [LYMPHOMAS]
- [TRANSLATIONAL IMMUNOMICS IN HEMATOLOGICAL NEOPLASMS]
Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
August 9, 2018 | Magazine: Journal of Medicinal ChemistryObdulia Rabal, Edurne San José-Enériz, Xabier Agirre, Juan Antonio Sánchez-Arias, Amaia Vilas-Zornoza, Ana Ugarte, Irene de Miguel, Estíbaliz Miranda, Leire Garate, Mario Fraga, Pablo Santamarina, Raul Fernandez Perez, Raquel Ordoñez, Elena Sáez, Sergio Roa, María José García-Barchino, José Angel Martínez-Climent, Yingying Liu, Wei Wu, Musheng Xu, Felipe Prosper, Julen Oyarzabal